This dataset provides histological cross sections of human vagus nerves that underwent immunohistochemistry (IHC) to label claudin-1 proteins, as well as binary traces following segmentation from which we quantified the effective nerve diameters, the effective fascicle diameters, the number of fascicles, and the perineurium thickness. These morphological data provide neural anatomical information, as well as foundational knowledge for computational and preclinical studies of vagus nerve stimulation. The dataset contains TIFF files for claudin-1 IHC micrographs and binary masks (nerve and fascicles) of 9 left cervical and 9 anterior subdiaphragmatic human vagus nerve samples, as well as a .mat file with the morphological output measures, totaling ~1 GB. Study purpose: To quantify human vagus nerve morphology Data collection: We conducted immunohistochemistry of paraffin-embedded human vagus nerve cross sections using an antibody against claudin-1. Using these micrographs, we quantified effective nerve and fascicle diameters, the number of fascicles, and the perineurium thickness at the cervical and subdiaphragmatic levels. These morphological data provide neural anatomical information, as well as foundational knowledge for computational and preclinical studies of vagus nerve stimulation. The dataset contains TIFF files for 9 left cervical and 9 anterior subdiaphragmatic human vagus nerve samples, providing segmented traces of inner and outer perineurial boundaries, as well as outer nerve boundaries.

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Showing: 1 - 20 of 20 items.